About
Contact Title
Vice President Architecture - Healthcare
Contact Company
Synergy Architecture Studio
Contact Profile/Bio
Matthew O’Keefe, AIA, NCARB, is a senior healthcare architecture executive with more than 25 years of experience leading complex medical projects and building high performing design practices. As Vice President of Architecture at Synergy Architecture Studio in Minneapolis, he is responsible for healthcare strategy, business development, and client engagement within an integrated real estate development platform. Since joining the firm’s founding team in 2019, Matthew has played a central role in scaling the practice to more than $1.6 million in annual billings and delivering over $250 million in healthcare projects, including outpatient surgery centers, medical office buildings, and medical tenant improvements.
A recognized leader in the healthcare market sector, Matthew brings a disciplined combination of executive design leadership, financial oversight, and operational insight to advancing healthcare environments. He is a frequent national speaker and trusted advisor to owners, developers, and operators navigating evolving healthcare delivery models and real estate strategies. Known for his clarity, credibility, and collaborative leadership style, Matthew partners with stakeholders to deliver resilient, efficient, and patient centered healthcare facilities.